MH Guide Labs

Evidently precise clinical interpretation on a new scale

MH Guide is an innovative new technology for diagnostic and pathology laboratories that perform cancer genome testing and want to automate clinical interpretation of test results, or outsource it to a specialist service provider.

Benefits for Labs

Intelligence

MH Guide automates the complex process of clinical interpretation. It gives you real-time insights into evidence of biomarker-drug information and enables patient-specific intelligence amplification for molecular pathology.

Significant

MH Guide distinguishes the significant clinically-actionable data points (signals) from irrelevant information (noise) in complex molecular data sets for individual patients.

Easy installation

MH Guide is easy to access, operate, and maintain. Molecular Health also offers application hosting and data storage.

Certification

MH Guide is registered as an in vitro diagnostic medical device (IVD) in Europe, conforms with the applicable European regulation (CE marked), and fulfills legal and regulatory requirements on validation and privacy (CAP, CLIA, HIPAA, ISO).

Up to date

MH Guide software, tools, methods, algorithms, and data are constantly updated, tested, and validated. And MH Guide is continuously improved with regular software and data updates.

Clinical context

For clinical interpretation of molecular diagnostic data, you need to understand the genetic make-up of the patient in a clinical context. MH Guide can help you.

Fast

Rapid, fully automated clinical, molecular, and pharmacologic workflow supplying a web-based interactive interpretation of patient data, within minutes of receipt of patient's VCF file.

Flexible

We can process BAM or FASTQ files, as well as VCF files. And we can provide a case-specific clinical molecular record in the form of an XML file, or you can use an online interface to prepare clinical reports in PDF-format, customized to your specifications.

Traceable

Deep dive into information sources. Our Dataome knowledge base contains expertly curated biomarkers of drug response, resistance, and toxicity, based on the world's biomedical literature and more than six million patient cases, allowing therapy options to be traced back to source.

Quality

We offer ethnicity-specific sequence analysis and can help you identify clinically relevant genomic aberrations. We compare these to biomarkers from the top global medical data sources and complete quality checks on all referenced biomarkers.

Scalable

Avoid interpretation bottlenecks. Our fully automated clinical, molecular, and pharmacologic workflows, fast VCF file interpretation, and web-based delivery of results mean we will always process cases efficiently.

Training

MH Guide comes with a full package of expert training and support to facilitate roll-out and implementation of the software in your organization as well as interpretation of the genetic analysis.

Authoritative

MH Guide information is sourced from approved, canonical medical knowledge, providing an authoritative basis for personalized treatment decisions.

Comprehensive

MH Guide contextualizes patient-specific molecular data against global biomolecular knowledge, using content drawn from more than six million patient cases.

Seamless integration into clinical routine practice through flexible interfaces

 
PATIENT SEQUENCE DATA AND DIAGNOSIS
FASTQ | VCF BAM+BED | ILLUMINA 
 
ADVANCED GENOME ANALYSIS
TUMOR | NORMAL
 
KNOWLEDGE MINING
OBSERVED | PREDICTED
 
CLINICAL INTERPRETATION
BIOMARKER | CASE
 
REPORTING / INTEGRATION
CLOUD | XML | PDF

Major components of MH Guide are:

Automated clinical data interpretation based on Dataome knowledge base
Flexible clinico-molecular data output interface

Our Dataome platform draws on the world's health knowledge

Molecular Health has built a comprehensive data warehouse that contains biomedical reference information of unique quality.