{"id":2667,"date":"2023-07-10T12:19:36","date_gmt":"2023-07-10T11:19:36","guid":{"rendered":"http:\/\/molecularhealth.com\/eu\/analysis-and-clinical-relevance-of-tumor-mutational-burden\/"},"modified":"2023-07-11T13:03:49","modified_gmt":"2023-07-11T12:03:49","slug":"analysis-and-clinical-relevance-of-tumor-mutational-burden","status":"publish","type":"post","link":"https:\/\/molecularhealth.com\/eu\/de\/analysis-and-clinical-relevance-of-tumor-mutational-burden\/","title":{"rendered":"Analysis and Clinical Relevance of Tumor Mutational Burden"},"content":{"rendered":"\n<p>Tumor mutational burden (TMB) is a genomic biomarker. In contrast to other biomarkers that are detected as a genomic alteration in a specific gene or via methods like immunohistochemistry, TMB is calculated. However, disagreements about calculation method, clinical indication for immunotherapy, and other factors have hindered establishment of TMB as a standardized biomarker. <\/p>\n<div class=\"lazyblock-mh-buttons-bar-Z22IFh3 wp-block-lazyblock-mh-buttons-bar\">  <section class=\"mh-buttons-bar\">\r\n          <a class=\"mh-buttons-item\" href=\"https:\/\/www.molecularhealth.com\/wp-content\/uploads\/MH-23-011-1_TMB-White-Paper_EN.pdf\" target=\"_self\"><i data-feather=\"arrow-right\"><\/i> <span>Zum Whitepaper<\/span><\/a>      <\/section>\r\n<\/div>","protected":false},"excerpt":{"rendered":"<p>Tumor mutational burden (TMB) is a genomic biomarker. In contrast to other biomarkers that are detected as a genomic alteration in a specific gene or via methods like immunohistochemistry, TMB is calculated. However, disagreements about calculation method, clinical indication for immunotherapy, and other factors have hindered establishment of TMB as a standardized biomarker.<\/p>\n","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","inline_featured_image":false,"footnotes":""},"categories":[35,49,46],"tags":[],"class_list":["post-2667","post","type-post","status-publish","format-standard","hentry","category-molecular-analysis-solutions-de","category-2023-de","category-whitepaper"],"acf":[],"_links":{"self":[{"href":"https:\/\/molecularhealth.com\/eu\/de\/wp-json\/wp\/v2\/posts\/2667","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/molecularhealth.com\/eu\/de\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/molecularhealth.com\/eu\/de\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/molecularhealth.com\/eu\/de\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/molecularhealth.com\/eu\/de\/wp-json\/wp\/v2\/comments?post=2667"}],"version-history":[{"count":3,"href":"https:\/\/molecularhealth.com\/eu\/de\/wp-json\/wp\/v2\/posts\/2667\/revisions"}],"predecessor-version":[{"id":2670,"href":"https:\/\/molecularhealth.com\/eu\/de\/wp-json\/wp\/v2\/posts\/2667\/revisions\/2670"}],"wp:attachment":[{"href":"https:\/\/molecularhealth.com\/eu\/de\/wp-json\/wp\/v2\/media?parent=2667"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/molecularhealth.com\/eu\/de\/wp-json\/wp\/v2\/categories?post=2667"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/molecularhealth.com\/eu\/de\/wp-json\/wp\/v2\/tags?post=2667"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}