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Rewiring Drug Research and Development through Human Data-Driven Discovery (HD3)
Jackson, D.B. et al. Pharmaceutics 2023, 15(6), 1673Open resourceWhole patient knowledge modeling of COVID-19 symptomatology reveals common molecular mechanisms
Brock, S. et al. Front. Mol. Med. 2023, 2:1035290. https://doi.org/10.3389/fmmed.2022.1035290Open resourceAdvancing drug safety science by integrating molecular knowledge with post‐marketing adverse event reports
Soldatos, T. G. et al. CPT Pharmacometrics Syst Pharmacol. 2022 May;11(5):540-555. doi: 10.1002/psp4.12765Open resourceApplication of a patient-centered reverse translational systems-based approach to understand mechanisms of an adverse drug reaction of immune checkpoint inhibitors
Kim, S. et al. Clin Transl Sci. 2022 Jun;15(6):1430-1438. doi: 10.1111/cts.13254Open resourceThe COVID-19 explorer – An integrated, whole patient knowledge model of COVID-19 disease
Brock, S. et al. Front. Mol. Med. 2022, 2:1035215. https://doi.org/10.3389/fmmed.2022.1035215Open resourceTarget adverse event profiles for predictive safety in the postmarket setting
Peter Schotland, Rebecca Racz, David B. Jackson, Theodoros G. Soldatos, Robert Levin, David G. Strauss and Keith Burkhart. Clinical Pharmacology & Therapeutics Volume 109, Issue 5, Pages: 1159-1362 (May 2021)Open resourceA case study of a patient-centered reverse translational systems-based approach to understand adverse event profiles in drug development
Kim, S. et al. Clin Transl Sci . 2022 Apr;15(4):1003-1013. doi: 10.1111/cts.13219Open resource